Role of immune factors in the pathogenesis of secretory otitis media

: Authors have been analysed the main role of immunological factors in complex pathogenesis of secretory otitis media. Data from recent literature and data from studies that were conducted in ENT city hospital in Belgrade were reviewed. The mucosa of the middle esr belong to the nasopharyngeal associated lymphoid tissue (NALT). The factors of the specific and non specific mucosal defence in middle ear mucosa can influence the mechanism of the chronic inflammation in secretory otitis media. The role of macrophages, mast cells, lymphoplasmocytes and adhesion molecules was emphasized. Concerning that results it is possible to create clinical studies in order improve the diagnostic procedures ant therapy of secretory otitis media.