Chromatographic packing for separating water soluble polymer and protein and preparation method of same

The present invention provides a hydrophilic chromatography on silica filler and a process for preparing water soluble polymer and the protein isolated. The preparation method comprises: A activated silica, activated silica gel was obtained; the activated B for epoxy-modified silicone, epoxy-modified silica gel prepared; C introduce hydrophilic groups on the epoxy-modified silicone polymers, polymer-modified silica gel prepared hydrophilic; D the hydrophilic polymer hydrolysis modifying silica, hydrophilic silica gel chromatography to obtain a water soluble polymer and a filler protein separation. The chromatographic material having a large pore volume, less hydrophobic, the higher the number of theoretical plates and larger peak capacity.