Method for in-situ construction of multistage nanometer topological structure on titanium-based implant surface based on salt corrosion

2016 
The invention discloses a method for in-situ construction of a multistage nanometer topological structure on a titanium-based implant surface based on salt corrosion. The method comprises the following steps: immersing pickled titanium or titanium alloy in a phosphate solution for low temperature heating treatment; performing heat treatment on the treated titanium or titanium alloy, washing with water and then drying to obtain a titanium-based implant with a multistage nanostructure formed on the surface. According to the method, salt solution is adopted as a medium to corrode titanium or titanium alloy, the titanium-based implant with the multistage nanostructure formed on the surface after heat treatment is obtained, conditions in the treatment process are mild, and no residue of strong acid or strong alkali exists; the formed multistage nanostructure has excellent biocompatibility, can promote the adhesion and growth of bone-related cells, and is expected to greatly improve the bone integration ability of the implant; the method can also be used in combination with other surface micrometer methods, can be used for constructing a micro-nanometer hybrid topological structure on the surface of the implant, and is expected to produce novel and efficient orthopedic implants and dental implants.
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