Clomiphene citrate treatment outcomes in Taiwanese hypogonadal men: A single-center preliminary report☆

Abstract Objective We evaluated the treatment efficacy of clomiphene citrate (CC) in hypogonadal men. Methods We retrospectively reviewed our patients with a diagnosis of hypogonadism who received CC treatment, and compared the pretreatment and post-treatment serum testosterone levels. Subjective patient improvements were recorded using the Androgen Deficiency in Aging Males questionnaire. Results A total of 10 patients were included in our analysis. Mean serum testosterone level increase from 246 ± 76 ng/dL to 548 ± 281 ng/dL was noted after treatment ( p 400 ng/dL after treatment. Conclusion CC is an effective alternative treatment for patients with hypogonadism.