Effects of acid-base correction on hemodynamics, oxygen dynamics, and resuscitability in severe canine hemorrhagic shock

Objective:To compare the effects of hypertonic saline, sodium bicarbonate, and Carbicarb® resuscitation on acid-base balance, hemodynamics, and oxygen dynamics in a reperfused, canine hemorrhagic shock model.Design:Prospective, randomized trial.Setting:Laboratory at a university medical center.Subje