1333 Clinical Manifestations of Urinary Tract Infections in Newborn Infants Admitted to Neonatal Intensive Care Unit

Background and Aims To determine the demography, clinical manifestations and the most common organism isolated of the urinary tract infection (UTI) in the newborn infants who were admitted to the neonatal intensive care unite (NICU). Methods Newborn infants diagnosed with UTI were investigated retrospectively, clinical and demographic characteristics of infants were collected from the medical records in the NICU. Urine cultures were obtained by suprapubic aspiration or urinary cathater. Results Fifty-one infants were included in this study. The mean (±SD) gestational age and weight of infants were 31.53±4.32 weeks, and 1724.90±902.21 g respectively. Male patients accounted for %56.9 of the study group. Infants born with cesarian section were %86.3. The median age for the urine culture was 31.53±4.3days. Klebsiella pneumania was the dominant microorganism isolated in 22 patients (43.13%), followed by Escherichia coli in 13 patients (25.4%). The most common presenting symptoms were vomitting in 39(76.5%) infants, desaturation in 34 (66.7%) infants, tachycardia in 31 (60.8%) infants, apnea in 21 (41.2%) infants and jaundice in 18 (35.3%) infants. Conclusions The incidence of UTI in newborn infants is 0.1–1% and it can be as high as 10% in low-birthweight and preterm babies. The presentation of UTI in the neonatal infants is non-specific and the most common clinical manifestations are vomitting, fever, enteral feeding intolerance, apnea and bradycardia. In this study, desaturation and tachycardia are also shown as presenting manifestations of UTI. Klebsiella pneumania was the dominant microorganism isolated in 22(43.13%) patients in our study.