Swelling and drug release from oral thin films (OTFs)

We investigate the characteristic time-scales for swelling and drug release from polymeric thin films for buccal delivery. In this work, novel OTFs were prepared combining Gellan gum, a natural polysaccharide well known in the pharmaceutical field, along with Glycerol, used as plasticizer. A new millifluidic flow-through device is adopted for in-vitro release tests.