Rv0174, Rv1729c and / or Rv3835 protein for the diagnosis of active tuberculosis preparing products
2013
The present invention provides Rv0174, Rv1729c or applications and / Rv3835 protein in the development and / or design having a differential, diagnosis, diagnosis, screening and / or secondary screening for active tuberculosis use products. The present invention also provides the use of Rv0174, Rv1729c and Rv3835 protein chip prepared. Protein chip prepared by the present invention, normal serum and three respective levels of IgG antibodies detecting active tuberculosis protein antigen, the corresponding antibodies conjoint detection results of these three proteins, it is determined whether or not the subject is a human activity tuberculosis, test results showed that specific protein chip diagnostic aid optimum operating point of active tuberculosis of the present invention to provide 82.2%, the sensitivity was 74.5%, higher than diagnostic indicators of active tuberculosis prior art.
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