Can Trace-Weighted Images Be Used to Estimate Diffusional Kurtosis Imaging–Derived Indices of Non-Gaussian Water Diffusion in Head and Neck Cancer?

We read with great interest the appealing article by Tu et al,[1][1] aimed at assessing the role of histogram-based descriptors of the non-Gaussian diffusional kurtosis imaging (DKI) model[2][2] in treatment-response prediction of nasopharyngeal carcinoma. They found that histogram-based analysis of