Study of Ag–Pd bimetallic nanoparticles modified glassy carbon electrode for detection of L-cysteine

Abstract Ag–Pd bimetallic nanoparticles (Ag–Pd BNPs) as an enhanced sensing material with improved electronic transmission rates in the electrochemical sensing of L -cysteine ( L -cys) has been reported. The morphology of Ag–Pd BNPs was characterized with X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM) and cyclic voltammetry (CV). Oxidation of L -cys on Ag–Pd BNPs is investigated in detail by discussing the effect of the structure and from the electrocatalytic oxidation of L -cys. We found that the Ag–Pd BNPs exhibited high electrocatalytic activity towards L -cys oxidation in neutral condition and could be used for the development of nonenzymatic L -cys sensor. Based on the efficient catalytic ability of Ag–Pd BNPs, the fabricated biosensor exhibited a wide linear range of responses to the L -cys with the concentration detection limit of nearly down to 2 mM with fast response time.