Abstract 11929: PAI-1 is Cardioprotective in Human Inflammatory Cardiomyopathy

Christian Baumeier,Felicitas Escher,Ganna Aleshcheva,Heiko Pietsch,Heinz-Peter Schultheiss

Abstract 11929: PAI-1 is Cardioprotective in Human Inflammatory Cardiomyopathy

2021

Christian Baumeier
Felicitas Escher
Ganna Aleshcheva
Heiko Pietsch
Heinz-Peter Schultheiss

Introduction: Preclinical data indicate that plasminogen activator inhibitor-1 (PAI-1) is cardioprotective by repressing fibrosis through TGF-β and plasminogen mediated pathways. Moreover, PAI-1 is...

Keywords:

preclinical data
Inflammation
Cancer research
Cardiomyopathy
Fibrosis
Plasminogen activator
Medicine

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