Synthesis of the Pentadecapeptide corresponding to the Entire Amino Acid Sequence of Salmon α-Melanotropin II (α-MSH II)

The pentadecapeptide corresponding to the entire amino acid sequence of α-MSH II, isolated from salmon pituitary gland, was synthesized by a conventional procedure. The synthetic peptide exhibited in vitro melanocyte-stimulating activity of 1.66×1010 MSH U/g.