MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1

Dengbo Ji,Zhiguo Chen,Ming Li,Tiancheng Zhan,Yunfeng Yao,Zhiqian Zhang,Jianzhong Xi,Li Yan,Jin Gu

MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1

2014

Dengbo Ji
Zhiguo Chen
Ming Li
Tiancheng Zhan
Yunfeng Yao
Zhiqian Zhang
Jianzhong Xi
Li Yan
Jin Gu

Background Given the emerging role of microRNA in tumor disease progression, we investigated the association between microRNA expression, liver metastasis and prognosis of colorectal cancer.

Keywords:

Vimentin
Beta-catenin
Biology
Cancer research
Colorectal cancer
microRNA
Epithelial–mesenchymal transition
Suppressor
Metastasis
Adenocarcinoma
Oncology
Internal medicine
Gene silencing
Gene expression profiling
Ectopic expression

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