Determination by 1D NOE studies of the stereochemistry of a tricyclic 2‐hydroxytetrahydrofuran derivative obtained by hydroformylation of (1R )‐(‐)‐myrtenol

The structure of a new, optically pure 2-hydroxytetrahydrofuran tricyclic compound resulting from the hydroformylation of (1R )-(−)-myrtenol was resolved by one- and two-dimensional 1H and 13C NMR. The configurations of the three new asymmetric centres are discussed on the basis of J(H,H) coupling constants, NOE measurements and molecular modelling. Copyright © 1999 John Wiley & Sons, Ltd.