Numerical and Experimental Investigations on Ring Resonator Type of Electrode for Circulating Tumor Cell Detection.

A ring resonator type of electrode to detect the circulating tumor cell (CTC) has been proposed because the early diagnosis can be performed and the cell condition can be investigated. Main emphasis was placed on the improvement of the Q-factor for high detection sensitivity. The low loss aluminum, Al membrane was deposited on the surface of the dielectric substrate and the thick copper, Cu was plated on the aluminum as the electrode thorough the lossy titanium, Ti as the adhesive. The Q-factor of the ring resonator was calculated to be about 100 at X-band frequencies thanks to the Al – Ti – Cu layered structure. To confirm the capability for the cell detection, the BaTiO 3 particles were inserted in the ring resonator type of electrodes instead of CTCs as preliminary experiment. The cell identification could be performed from the numerically and experimentally investigations.