A Novel Epigenetic Phenotype Associated With the Most Aggressive Pathway of Bladder Tumor Progression

Céline Vallot,Nicolas Stransky,Isabelle Bernard-Pierrot,Aurélie Hérault,Jessica Zucman-Rossi,Elodie Chapeaublanc,Dimitri Vordos,Agnès Laplanche,Simone Benhamou,Thierry Lebret,Jennifer Southgate,Yves Allory,François Radvanyi

A Novel Epigenetic Phenotype Associated With the Most Aggressive Pathway of Bladder Tumor Progression

2011

Céline Vallot
Nicolas Stransky
Isabelle Bernard-Pierrot
Aurélie Hérault
Jessica Zucman-Rossi
Elodie Chapeaublanc
Dimitri Vordos
Agnès Laplanche
Simone Benhamou
Thierry Lebret
Jennifer Southgate
Yves Allory
François Radvanyi

Background Epigenetic silencing can extend to whole chromosomal regions in cancer. There have been few genome-wide studies exploring its involvement in tumorigenesis.

Keywords:

Cancer
Gene silencing
DNA methylation
Bladder cancer
Phenotype
Immunology
Tumor progression
Epigenetics
Carcinogenesis
Biology

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