Abstract 13483: Insulin-Like Growth Factor Binding Protein 2 Overexpression Leads to Aortic Hypocontractility Through Vascular Smooth Muscle Phenotypic Switching

Introduction: Insulin-like growth factor binding proteins (IGFBP) exhibit multiple effects beyond regulation of IGFs. IGFBP2 is upregulated in vascular smooth muscle cells (VSMC) in human atheroscl...