Recent Advances of Electrochemiluminescent System in Bioassay

Electrochemiluminescent (ECL) technique has drawn increasing attention in a myriad of applications ranging from clinic diagnosis to the environment and food monitoring. The advantages of ECL sensors include high sensitivity, negligible background, and excellent controllability with respect to its counterparts. The past 2 years have witnessed an impetus in the rise of a batch of luminophores and coreactants as advanced materials to boost the ECL efficiencies. In the review, we summarize the latest progress of new ECL biosensing systems, in particular of emerging luminophores, coreactants, and the involved mechanisms. Possible limitations and exciting future developments of the ECL biosensing are also complementarily discussed. It is highly envisioned that the review article would inspire more intriguing advances both in the fundamental research and more demanding practical applications of ECL for prospective biosensing.