Using Comparative Genomics to Explore the Genetic Code of Influenza Virus of 1918

Run a multiple sequence alignment using H3N2, H1N1 and H5N1 influenza A viral sub- H1N1 and H5N1 influenza A viral sub- strains. strains. • Use the sequence alignment to construct a phylogenetic tree. Use the sequence alignment to construct a phylogenetic tree. • The 8 RNA molecules: The HA gene. It encodes the hemaglutinin. 3 distinct hemaglutinins, H1, H2, and H3) are found in human infections; • The NA gene. It encodes the neuraminidase. 2 different neuraminidases (N1 and N2) have been found in human viruses; • The NP gene encodes the nucleoprotein. Influenza A, B, and C viruses have different nucleoproteins.