GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas

Yurie Mikami,Shinsuke Fujii,Kengo Nagata,Hiroko Wada,Kana Hasegawa,Misaki Abe,Reiko U. Yoshimoto,Shintarou Kawano,Seiji Nakamura,Tamotsu Kiyoshima

GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas

2017

Yurie Mikami
Shinsuke Fujii
Kengo Nagata
Hiroko Wada
Kana Hasegawa
Misaki Abe
Reiko U. Yoshimoto
Shintarou Kawano
Seiji Nakamura
Tamotsu Kiyoshima

Purpose Keratin 17 (KRT17) has been suggested as a potential diagnostic marker of squamous cell carcinoma including oral squamous cell carcinoma (OSCC). The current study was conducted to clarify the function of KRT17 and its expression mechanism in OSCC.

Keywords:

Cell
Immunology
Carcinoma
Keratin 5
Cancer research
Apoptosis
Keratin 17
Cell growth
Oncology
Internal medicine
Keratin 8
Biology
diagnostic marker
Hematology
tumor cells
Pathology

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