Compound drug for drug-loaded balloon for diseased artery vasodilatation and drug-loaded balloon

Disclosed are a compound drug for a drug-loaded balloon for diseased artery vasodilatation and the drug-loaded balloon. The compound drug comprises the following raw materials: a lipophilic active drug for treating arterial blood vessel diseases, a drug complexing agent and a solvent. The mass ratio of the active drug to the drug complexing agent is 1.2-4.8, the mass volume ratio of the total mass of the active drug and drug complexing agent to the solvent is 8-20 (g/l), the drug complexing agent is a hydrophilic surfactant, and the solvent is a non-polar solvent miscible with water, or a mixed solution of a non-polar solvent miscible with water and water. The drug-loaded balloon is a balloon comprising a folded flap structure, a drug coating is attached to the surface of the balloon, and the drug coating comprises an active drug and a drug complexing agent.