Novel synthetic route to perfluoroallyl cyanide (PFACN) reacting perfluoroallyl fluorosulfonate with cyanide

Abstract A novel synthetic method for the preparation of perfluoroallyl cyanide CF 2 CFCF 2 CN (PFACN) is presented. This includes the addition – elimination reaction of cyanide anion with perfluoroallyl fluorosulfate CF 2 CFCF 2 OSO 2 F (PFAFS). The reaction conditions, factors affecting the reactivity and regioselectivity of the process, the choice of reagent as well as the course of competitive reactions are discussed, too.