Tumor colorrectal de células granulares: presentación de dos casos y revisión de la literatura

Los tumores de celulas granulares (Abrikossoff) son tumores estromales benignos que se manifiestan mas frecuentemente en la cabeza y cuello. La ubicacion colorrectal es menos frecuente. Presentamos 2 casos de ubicacion colorrectal. En el primer caso se trato de un tumor ubicado en el recto bajo, a 4 cm del margen anal, que se reseco mediante tecnica transanal. El siguiente caso se ubico en el ciego y, ante la falta de exeresis endoscopica, se reseco mediante hemicolectomia derecha laparoscopica. Ambos tuvieron diagnostico histopatologico de Tumor de Celulas Granulares (TCG) confirmado por inmunohistoquimica. Los TCG son tumores generalmente benignos con caracteristicas inequivocas en el estudio histologico (abundante citoplasma eosinofilo, nucleos pequenos, uniformes y redondos, sin mitosis evidentes) e inmunohistoquimico (PAS y proteina S-100 positivas). Aparecen entre la 4a y 6a decada en cualquier parte del organismo. En el tubo digestivo aparecen mas frecuentemente en el esofago. Debe sospecharse su presencia ante la aparicion de un nodulo submucoso solido, menor de 2 cm, y generalmente unico. Granular cell tumors (Abrikossoff) are benign stromal tumors that usually appear in the head and neck. Colorectal location is less frequent. We present two clinical cases in this location. The first patient presented with a tumor located in the lower rectum, 4 cm from the anal verge, which was resected via local excision. The second case was located in the cecum, and it was resected by laparoscopic right colectomy. Both cases had histopathology diagnosis of Granular cell tumors (GCT) confirmed by immunohistochemistry. GCT are usually benign tumors with unequivocally features in histological analysis (abundant-eosinophilic cytoplasm, small nuclei, round and uniform, without evident mitoses) and immunohistochemichal staining (PAS and S-100 protein positive). The age of presentation is around 4th and 6th decades at any part of the body. In the digestive tract they grow more frequently at the esophagus. Diagnosis should be suspected when facing a unique, solid, less than 2 cm submucosal nodule.