Determination of the Microstructure of Decellularized Dermal Scaffolds

One of the most important aspects of regenerative medicine is the selection of the scaffold—the biological skeleton of the tissue-engineering structure. To reproduce the structure and properties of damaged tissue and maintain the cell adhesion and proliferation, it is optimal to use scafflds obtained by decellularization of native organs with subsequent recellularization of various cell lines. Using the methods of environmental scanning electron microscopy and scanning pulsed ultrasound microscopy, the microstructure of native and decellularized matrixes of dermal tissues was determined.