Abstract 20519: Effects of Obstructive Sleep Apnea on the Outcomes of Atrial Fibrillation: A Nationwide Analysis

Introduction: Recent studies suggest patients with atrial fibrillation (AF) who suffer from obstructive sleep apnea (OSA) have varied responses to ablative procedures, as AF substrates in these patients might be different from patients with primary AF. We investigated the effects of coexistence of these two conditions on mortality and hospital costs in patients who underwent AF ablation. We hypothesized there would be significant differences in mortality between the two populations. Methods: This is a retrospective cohort study using the 2013 National Inpatient Sample (NIS) of males and females over 18 hospitalized with AF who underwent ablation, based on ICD-9 codes. The population was divided into patients with and without a concomitant diagnosis of OSA. The primary outcome was all cause inpatient mortality and secondary outcomes were mean length of stay (LOS), and total hospital costs. The multivariate logistic regression model was used to adjust for potential confounders including age, gender, race, h...