ANTIPROLIFERATIVE EFFECTS OF SOME MEDICINAL PLANTS ON HELA CELLS
2013
Medicinal plants maintain the health and vitality of individuals, and also
have potential curative effect on various diseases, including cancer. In this
study were investigated the antiproliferative effects of water extracts of
previously obtained ethanolic dry extracts of three different medicinal
plants (Echinacea angustifolia, Salvia officinalis and Melissa officinalis)
on cell lines derived from human cervix adenocarcinoma (HeLa cells). The best
cytotoxic activity (IC50 = 43.52 μg/ml) on HeLa cell lines was exhibited by
Echinacea angustifolia. The extract of Salvia officinalis also showed a good
cytotoxic activity against HeLa cell lines; the IC50 value was 70.41 μg/ml.
Melissa officinalis manifested a slightly weaker cytotoxic activity and an
IC50 value of 122.22 μg/ml. [Projekat Ministarstva nauke Republike Srbije,
br. 34021 i br. 175011]
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