Multiple Endocrine Neoplasia Type 1 Presenting with Hypoglycemia due to Insulinoma: A Case Report
2018
Multiple Endocrine neoplasia type 1 is a rare, autosomal dominant disorder consisting of tumors of the parathyroid, pancreatic islets, and anterior pituitary. The incidence of insulinoma in multiple endocrine neoplasia is relatively uncommon. However, insulinoma is the most common cause of hyperinsulinemic hypoglycemia. We report a case of a 38-year-old female who presented to the emergency department because of frequent attacks of hypoglycemia in the form of diaphoresis, loss of consciousness, and tonic-clonic seizures. Parathyroidectomy was performed for her when she was 10 years old. After the biochemical and radiological investigation, she has been diagnosed with Multiple Endocrine neoplasia type 1 due to the presence of insulinoma, parathyroid adenoma, and a pituitary microdenoma. Insulinoma is a rare condition, however it should be encountered in the differential diagnosis of any young individual presenting with frequent hypoglycemic symptoms.
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