Substituted propanamide derivatives and pharmaceutical compositions containing them

It is an object of the present invention to provide a substituted propanamide derivative or a pharmacologically acceptable salt thereof that is useful as a prophylactic or therapeutic agent for a bone metabolic disease. The present invention relates to a pharmaceutical composition comprising a compound having General Formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein, R 1 represents a C 6 -C 10 aryl group that may be substituted by a group selected from Substituent Group ±, for example; R 2 represents a C 6 -C 10 aryl group that may be substituted by a group selected from Substituent Group ±, for example; and X represents a hydroxyl group or a C 1 -C 6 alkoxy group, for example].