Development of a New Heterogeneous Lewis Acid Catalyst for Chemoselective Tetrahydropyranylation of Different Hydroxyl Compounds

Amino functionalized triazine supported on silica-gel was prepared and characterized. This new triazine derivative was applied as a coordinating agent for aluminum chloride. This novel Lewis acid supported on heterogeneous surface was used as an effective catalyst for protection of alcohols and phenols in the presence of 3,4-dihydro-2H-pyran. This catalyst can be reused without any significant loss of activity, and it protects alcohols in the presence of phenols.