high-purity daptomycin lactone hydrolysate and its application

2016 
The invention discloses a kind of high-purity daptomycin lactone hydrolysate, prepare and its application.The problem of present invention solves big mobile phase consumption when Daptomycin lactone hydrolysate is prepared using the method for preparing post separation in the prior art, production cycle length, complex operation, low yield and high cost.High-purity daptomycin lactone hydrolysate disclosed by the invention can be used for the detection of Daptomycin, it is achieved thereby that effectively control Daptomycin quality, it is ensured that the drug safety of Daptomycin.
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