ONE POT BF3.MeCN CATALYZED SOLVENT FREE SYNTHESIS OF 3,4-DIHYDROPYRIMIDINE-2-ONE ANALOGUES

One-pot solvent free three components coupling of aryl aldehydes, β-dicarbonyl compounds, urea or thiourea was performed to afford corresponding 3,4-dihydropyrimidine-2-ones and their sulfur analogs 3,4-dihydro-pyrimidine-2-thiones. It is the first report of BF 3 .ACN catalyzed the solvent-free synthesis of pyrimidone analogs.