Compressional Properties of Cyclodextrins

There is little information about powder and binding properties of cyclodextrins (CDs). The earliest paper in relation with binding properties of a s-cyclodextrin polymer pilot product was published by Fenyvesi et al. (1984). The s-cyclodextrin polymer was found to be well suitable for direct compression, owing to its relatively advantageous binding and disintegration properties. Giordano et al. (1990) and more recently Pande and Shangraw (1995) studied the compaction capacity of sCD and the influence of water content.