Hexane metabolites (2,5‐ Hexanedione, 2‐Hexanone) [Biomonitoring Methods, 1994]

Published in the series Analyses of Hazardous Substances in Biological Materials, Vol. 4 (1994) The article contains sections titled: General principles Equipment, chemicals and solutions Equipment Chemicals Solutions Calibration standards Preparation of the XAD extraction columns Preparation of the cation exchange columns Specimen collection and sample preparation Sample preparation with hydrolysis (to determine the total content of 2,5-hexanedione as well as 2-hexanone) Sample preparation without hydrolysis (to determine the freely extractable 2,5-hexanedione as well as 2-hexanone) Operational parameters for gas chromatography Analytical determination Calibration Calculation of the analytical result Standardization and quality control Reliability of the method Precision Accuracy Detection limit Sources of error Discussion of the method Keywords: determination in urine; capillary gas chromatography; analysis in biological materials; occupational monitoring; analytical method; biomarker; metabolites