Thermo-luminescent dosimeter evaluation of extra-target dose in intensity modulated sequential tomotherapy for pancreatic cancer

The proximity of abdominal tumors to non-target organs has motivated exploration of intensity modulated radiation therapy (IMRT), with its demonstrated capability to create conformal dose gradients, in abdominal tumors. However, substantial extra-target dose may be observed to radiosensitive organs remote from the treatment field. We present dosimetric data from two patients receiving abdominal IMRT using a sequential tomotherapy technique, demonstrating substantial dose to extra-target organs.