Gemcitabine-based neoadjuvant chemotherapy for locally advanced pancreatic cancer does not affect mortality and morbidity after pancreatic resection

Background Neoadjuvant strategies for locally advanced pancreatic cancer (PC) have been increasingly studied over the last decade. The effect of only systemic chemotherapy on postoperative morbidity and mortality remains unclear. The objective of this study was to determine the risk of postoperative complications in patients undergoing pancreatic resection for locally advanced, nonmetastatic PC following neoadjuvant gemcitabine-based chemotherapy.