Design and evaluation of glutathione responsive glycosylated camptothecin nanosupramolecular prodrug.

Wenhua Li,Zhong Chen,Xiaoying Liu,Mingming Lian,Haisheng Peng,Changmei Zhang

Design and evaluation of glutathione responsive glycosylated camptothecin nanosupramolecular prodrug.

2021

Wenhua Li
Zhong Chen
Xiaoying Liu
Mingming Lian
Haisheng Peng
Changmei Zhang

A novel tumor-targeted glutathione responsive Glycosylated-Camptothecin nanosupramolecular prodrug (CPT-GL NSp) was designed and fabricated via a disulfide bond. The effects of glycoligand with dif...

Keywords:

Stereochemistry
Chemistry
Camptothecin
Glutathione
Prodrug
Disulfide bond

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