Aminoglycosides suppress the protein folding activity of the molecular chaperone HSC70: implication of a structure-activity relationship.

Soh Yamamoto,Hideki Wakui,Hiroshi Kubota,Atsushi Komatsuda,Hideaki Itoh,Shin-ichi Yokota

Aminoglycosides suppress the protein folding activity of the molecular chaperone HSC70: implication of a structure-activity relationship.

2014

Soh Yamamoto
Hideki Wakui
Hiroshi Kubota
Atsushi Komatsuda
Hideaki Itoh
Shin-ichi Yokota

Background: The mechanism of aminoglycoside (AG)-induced nephrotoxicity has not been fully elucidated. We previously reported that gentamicin suppresses the funct

Keywords:

Chaperone (protein)
Aminoglycoside
Biology
Protein folding
Nephrotoxicity
Structure–activity relationship
Molecular biology
Gentamicin
Paromomycin
Streptomycin
Neomycin
Ribostamycin
Sisomicin
Biochemistry
Arbekacin

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations