Activation of Antigen-Specific CD8 + T Cells by Poly-DL-Lactide/Glycolide (PLGA) Nanoparticle-Primed Gr-1 high Cells

Purpose The aim of this study was to investigate the induction of antigen-specific T cell activation and cell cycle modulation by a poly-DL-lactide/glycolide (PLGA) nanoparticle (NP)-primed CD11b+Gr-1high subset isolated from mouse bone marrow.