Long-term efficacy and safety of daylight photodynamic therapy with methyl amninolevulinate for actinic keratosis of the face and scalp

Daylight-photodynamic therapy (DL-PDT) with methyl aminolevulinate (MAL) is an EMA-approved simplified PDT procedure for mild-to-moderate actinic keratosis (AK) using natural daylight instead of an artificial light source, associated with similar efficacy and improved tolerability relative to conventional PDT (c-PDT) in short-term comparison trials [1-6]. However, long-term follow-up data are not available from these trials.We recently reported an intra-patient comparison study showing that DL-PDT [...]