Some Electrophysiological and Hemodynamic Characteristics of the Processes of Auditory Selective Attention in Health and Schizophrenia

Six patients in remission after first episodes of juvenile schizophrenia and seven mentally healthy subjects selected on the basis of age and gender were studied by functional magnetic resonance imaging and recording of evoked potentials, in both cases using the oddball paradigm in the auditory modality. Differences in the parameters of the P300 wave were significant, and significantly greater hemodynamic responses to test stimuli were recorded bilaterally in the supramarginal gyrus and right medial frontal gyrus in patients, pointing to pathology in these areas of the brain in their support for auditory selective attention processes.