Evaluation of the Transforming Growth Factor β Activity in Normal and Dry Eye Human Tears by CCL-185 Cell Bioassay

Xiaofen Zheng,Cintia S. De Paiva,Kavita Rao,De-Quan Li,William J. Farley,Michael E. Stern,Stephen C. Pflugfelder

Evaluation of the Transforming Growth Factor β Activity in Normal and Dry Eye Human Tears by CCL-185 Cell Bioassay

2010

Xiaofen Zheng
Cintia S. De Paiva
Kavita Rao
De-Quan Li
William J. Farley
Michael E. Stern
Stephen C. Pflugfelder

Purpose To develop a new bioassay method using human lung epithelial cells (CCL-185) to assess activity of transforming growth factor beta (TGF-β) in human tear fluid from normal subjects and patients with dry eye.

Keywords:

Dry Eye Syndromes
Cell
Cell growth
Pathology
Tears
Transforming growth factor
Transforming growth factor beta
Cell culture
Medicine
Bioassay
Mink
Biology
Lung

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