The Formation of Heterodimers by Vancomycin Group Antibiotics

Thomas Staroske,Dominic P. O’Brien,Thomas J.D. Jørgensen,Peter Roepstorff,Dudley H. Williams,Albert J. R. Heck

The Formation of Heterodimers by Vancomycin Group Antibiotics

2000

Thomas Staroske
Dominic P. O’Brien
Thomas J.D. Jørgensen
Peter Roepstorff
Dudley H. Williams
Albert J. R. Heck

The formation of heterodimers (see diagram) in mixtures of glycopeptide antibiotics are investigated by electrospray ionization mass spectrometry (ESI-MS) and NMR spectroscopy. Dimerization constants are determined.

Keywords:

Nuclear magnetic resonance spectroscopy
Organic chemistry
Glycopeptide
Chemistry
Electrospray ionization
Vancomycin
Antibiotics
Mass spectrometry
Chromatography
Inorganic chemistry
Aqueous solution

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