Alfacalcidol injection and preparation method thereof
2015
The invention relates to an alfacalcidol injection and a preparation method thereof. The injection is prepared from the following ingredients by weight percent: 0.0005 percent of alfacalcidol, 1.2-1.6 percent of polyvinylpyrrolidone K30, 18-24 percent of hydroxypropyl cellulose aqueous solution, 1.2-1.7 percent of sodium dodecyl sulfate, 0.1 percent of an antioxygen, a moderate amount of an isoosmotic adjusting agent, and the balance of water for injection. The content of alfacalcidol in the preparation is remarkably increased; the medicine dose is decreased; the stability of alfacalcidol for light and air is improved; the bioavailability of alfacalcidol is remarkably improved as well.
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