Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences

Bo Cao,Chao Chen,Michael S. DeMott,Qiuxiang Cheng,Tyson A. Clark,Xiaolin Xiong,Xiaoqing Zheng,Vincent Butty,Stuart S. Levine,George Yuan,Matthew Boitano,Khai Luong,Yi Song,Xiufen Zhou,Zixin Deng,Stephen Turner,Jonas Korlach,Delin You,Lianrong Wang,Shi Chen,Peter C. Dedon

Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences

2014

Phosphorothioate (PT) DNA modifications are widespread in bacteria and play a critical role in cell physiology. Here, the authors develop two sequence-based technologies to map PT modifications across bacterial genomes.

Keywords:

Consensus sequence
Bioinformatics
Biology
Computational biology

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