Esomeprazole magnesium enteric-coated tablet containing esomeprazole magnesium pellets and preparation method of esomeprazole magnesium enteric-coated tablet

The invention belongs to the field of medicines and discloses an esomeprazole magnesium enteric-coated tablet containing an esomeprazole magnesium pellet and a preparation method of the esomeprazole magnesium enteric-coated tablet. The enteric-coated tablet is prepared by pressing pellets taking esomeprazole magnesium as active components, a thinner, a disintegrating agent, a lubricating agent and the like. According to the method provided by the invention, an enteric-coated pellet is firstly made into a medicine contained core pellet and then is sequentially wrapped with an insulating layer, an enteric coated layer and a wax protecting layer. According to the tablet provided by the invention, the enteric-coated pellet is wrapped with the wax protecting layer, so that the problems of acid tolerance descending caused by the breakage of the enteric coated layer during the tabletting process of the enteric-coated pellet, and disqualification in content uniformity caused by excess liquidity can be solved.