Application of combination of atractyloside and 5-fluorouracil in preparation of medicine for prevention and therapy of rectal cancer

2016 
The invention discloses an application of combination of atractyloside and 5-fluorouracil in preparation of a medicine for prevention and therapy of rectal cancer. The effect of inhibition on colorectal cancer cells by combination of the atractyloside and 5-fluorouracil is significantly better than that by single application of the 5-fluorouracil, so that the combination of the atractyloside and 5-fluorouracil can effectively inhibit proliferation of the colorectal cancer cells and is very suitable for preparation of the medicine for prevention and therapy of the rectal cancer. The medicine can effectively inhibit the proliferation of the colorectal cancer cells. The application effectively improves the curative effect of the clinical chemotherapy medicine 5-fluorouracil, thus controlling development and metastasis of the colorectal cancer. The in-vitro colorectal cancer cell proliferation inhibition method can be used for guiding establishment of an in-vivo colorectal cancer cell therapy method.
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