P115 The influence of maternal IBD on childbirth and further development of children

patient year for the above BMI categories, respectively (p = 0.36). Neither the courses of steroids (per patient year), proportion of patients receiving more than 3 courses of steroids in their lifetime, or the proportion of patients requiring immunosuppressant or biologic medication, differed significantly between the two groups The median time-to-firstuse of anti-TNF (in months) was 14 (range 3 120), 36 (3 504) and 24 (4 600) in the above BMI categories, respectively (p 30 nearing the national average of 26% (source: Office of National Statistics 2012). Obesity is associated with colonic disease location, less penetrating disease, but no difference in the rates of stricturing disease or of operative intervention. Our data also imply a more aggressive inflammatory phenotype in terms of requiring biologic therapy significantly earlier in the natural history of disease. The mechanism for these effects is unclear, but environmental and luminal factors could be critical.