Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

Xiwen Xiong,Gaihong Wang,Rongya Tao,Pengfei Wu,Tatsuyoshi Kono,Kevin Li,Wen-Xing Ding,Xin Tong,Sarah A. Tersey,Robert A. Harris,Raghavendra G. Mirmira,Carmella Evans-Molina,X. Charlie Dong

Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

2016

Xiwen Xiong
Gaihong Wang
Rongya Tao
Pengfei Wu
Tatsuyoshi Kono
Kevin Li
Wen-Xing Ding
Xin Tong
Sarah A. Tersey
Robert A. Harris
Raghavendra G. Mirmira
Carmella Evans-Molina
X. Charlie Dong

Aims/hypothesis Sirtuin 6 (SIRT6) has been implicated in ageing, DNA repair and metabolism; however, its function in pancreatic beta cells is unclear. The aim of this study is to elucidate the role of SIRT6 in pancreatic beta cells.

Keywords:

Sirtuin
Insulin
Secretion
Insulin receptor substrate
Beta cell
Endocrinology
Carbohydrate metabolism
Internal medicine
Mitochondrion
Diabetes mellitus
Chemistry
SIRT6
Calcium

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations