Abstract P6-02-09: Bahcesehir mammography screening project (BMSP) is cost-effective in a developing country

Objective: This study aims to determine the cost-effectiveness of a population-based organized mammography screening in a developing country (Bahcesehir, Istanbul, Turkey). Material and methods: Between 2009 and 2015, mammographies were obtained by 2-year intervals for women with ages 40-69 years (n=7167), living in Bahcesehir.. Cost for BMSP included salaries paid for the staff, purchase and maintenance of diagnostic devices, and cost of diagnosis, treatment and follow-up of detected breast cancer patients. The incremental cost-effectiveness ratio (ICER) was calculated as the extra expense per extra "life year" saved by BMSP, when compared to breast cancer detected without screening (BCWS). ICER=CostBMSP-CostBCWS/Life-yearsBMSP – Life-yearsBCWS.Gross Domestic Product per capita in Turkey in 2014 was found (10.650 USD). According to WHO, ICER value below GDP per capita is defined cost-effective. Results Of 7167 women, 67 were diagnosed with breast cancer after the third screening round. Stages of BC patients diagnosed in BMSP and national breast cancer registry program (NBRP), expected 5 year survival rates and expected median survival life according to stages, and stage distribution of patients were shown in Table 1. Median expected life time of patients in screening group was 5.87 years longer than patients in NBRP (21.50 years vs 15.63 years), and, totally 393 years were saved with BMSP. Additionally, 71 months of workload were saved with mammography screening (Table 2). The incremental cost-effectiveness ratio (ICER) was found 1.897 USD/year. Since ICER/year has been calculated to be less than PDG per capita (10.650 USD), BMSP definitely seems to be cost-effective. Conclusion Population-based mammography screening results in early detection of breast cancer, and seems to be cost-effective in Bahcesehir Mammography Screening Program in Turkey. Our findings also suggest that a nation wide organized population- based screening paid by National Social Security Institute in Turkey might be more cost-effective than BMSP. Citation Format: Ozmen V, Cabiogsu N, Ozkan-Gurdal S, Ozaydin N, Kayhan A, Aribal E. Bahcesehir mammography screening project (BMSP) is cost-effective in a developing country. [abstract]. In: Proceedings of the Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2015 Dec 8-12; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2016;76(4 Suppl):Abstract nr P6-02-09.