Vitamin D Supplementation During Pregnancy and Infancy Reduces Aeroallergen Sensitization: A Randomized Controlled Trial

ML Grant, J Crane, EA Mitchell. Allergy. 2016;71(9):1325–1334 To determine whether vitamin D supplementation during pregnancy and infancy prevents aeroallergen sensitization and respiratory illness identified by primary care providers. Two hundred and sixty women were recruited from an urban primary care maternity clinic in New Zealand from April 2010 to July 2011. The women were managed from 27 weeks’ gestation to delivery, and their infants were managed from birth to 18 months of age. Participants were not taking vitamin D supplementation before enrollment. This was a randomized, double-blind, placebo-controlled, parallel-group trial. The mother and infant pairs were randomly assigned …